A Tragic Consequence of Research Misconduct
Author: Ronald J. Comer
Princeton University
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This video focuses on the case of a man with schizophrenia who died after participating in an experimental drug trial at an inpatient treatment facility. Given the man's background and mental illness, as shown in the video, consider as you watch whether he was able to make decisions relating to his own treatment. As you will see from the video, there are many questions about the ethics of research using severely mentally ill patients for experimental drug trials. As you watch, you might consider the implications of such practices for the patients and their families.
1. In the video case, Joseph underwent a ________________ study, a type of research, which, in his case, led to his death.
2. In the video case of Joseph, at the heart of the controversy is the question of whether his research study actually involved ______________.
3. In the scandalous __________ clinical study, mentally challenged young children were deliberately infected with hepatitis to help find a cure for hepatitis. When this study was exposed in the 1970s, it helped lead to the National Research Act of 1974.
4. In some placebo studies, __________ are administered to the control groups instead of actual placebos.
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