Brown adipose tissue is revealed on exposure to cold. The results of PET–CT scanning show the uptake and distribution of18F-fluorodeoxyglucose (18F-FDG) in adipose tissue. The patterns of18F-FDG uptake in the same subject are dramatically different under thermoneutral conditions (A) and after exposure to cold (B).
[Republished with permission of American Society for Clinical Investigation from J Clin Invest. 2013;123(8):3395–3403. doi:10.1172/JCI68993. Permission conveyed through Copyright Clearance Center, Inc.]