Table 18.2: Components of the mitochondrial electron-transport chain
    

Oxidant or reductant

Enzyme complex

Mass (kDa)

Subunits

Prosthetic group

Matrix side

Membrane core

Cytoplasmic side

NADH-Q oxidoreductase

>900  

46

FMN

Fe-S

NADH

Q

 

Succinate-Q reductase

140

  4

FAD

Fe-S

Succinate

Q

 

Q-cytochrome c oxidoreductase

250

11

Heme bH

Heme bL

Heme c1

Fe-S

 

Q

Cytochrome c

Cytochrome c oxidase

160

13

Heme a

Heme a3

CuA and CuB

  

Cytochrome c

Information from: J. W. DePierre and L. Ernster, Annu. Rev. Biochem. 46:215, 1977; Y. Hatefi, Annu Rev. Biochem. 54:1015, 1985; and J. E. Walker, Q. Rev. Biophys. 25:253, 1992.