Table 22.1: Principal reactions in fatty acid oxidation

Step

Reaction

Enzyme

1

Acyl CoA synthetase (also called fatty acid thiokinase and fatty acid:CoA ligase)*

2

Carnitine acyltransferase (also called carnitine palmitoyl transferase)

3

Acyl CoA dehydrogenases (several isozymes having different chain-length specificity)

4

Enoyl CoA hydratase (also called crotonase or 3-hydroxyacyl CoA hydrolyase)

5

l-3-Hydroxyacyl CoA dehydrogenase

6

β-Ketothiolase (also called thiolase)

*An AMP-forming ligase.