Disease | Selected Genes | Repair Pathway |
---|---|---|
Xeroderma pigmentosum (skin) | XPA, XPB, XPC | Nucleotide excision repair |
Lynch syndrome (colon cancer) | MSH2, MLH1 | Mismatch repair |
Breast and ovarian cancer | BRCA1 and BRCA2 | Doubl |
Renal and lung cancer | OGG1 | Base excision repair |