Table 8.7: Enzymes for which kcat/KM is close to the diffusion-controlled rate of encounter

Enzyme

kcat/KM (s−1 M−1)

Acetylcholinesterase

1.6 × 108

Carbonic anhydrase

8.3 × 107

Catalase

   4 × 107

Crotonase

2.8 × 108

Fumarase

1.6 × 108

Triose phosphate Isomerase

2.4 × 108

β-Lactamase

   1 × 108

Superoxide dismutase

   7 × 109

Source: Information from A. Fersht, Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding (W. H. Freeman and Company, 1999), Table 4.5.