Where to Start
Zalatan, J. G., and Herschlag, D. 2009. The far reaches of enzymology. Nat. Chem. Biol. 5:516–
Hammes, G. G. 2008. How do enzymes really work? J. Biol. Chem. 283:22337–
Koshland, D. E., Jr. 1987. Evolution of catalytic function. Cold Spring Harbor Symp. Quant. Biol. 52:1–
Jencks, W. P. 1987. Economics of enzyme catalysis. Cold Spring Harbor Symp. Quant. Biol. 52:65–
Lerner, R. A., and Tramontano, A. 1988. Catalytic antibodies. Sci. Am. 258(3):58–
Cook, P. F., and Cleland, W. W. 2007. Enzyme Kinetics and Mechanism. Garland Press.
Fersht, A. 1999. Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding. W. H. Freeman and Company.
Walsh, C. 1979. Enzymatic Reaction Mechanisms. W. H. Freeman and Company.
Bender, M. L., Bergeron, R. J., and Komiyama, M. 1984. The Bioorganic Chemistry of Enzymatic Catalysis. Wiley-
Abelson, J. N., and Simon, M. I. (Eds.). 1992. Methods in Enzymology. Academic Press.
Friedmann, H. C. (Ed.). 1981. Benchmark Papers in Biochemistry, vol. 1, Enzymes. Hutchinson Ross.
Schramm, V. L. 2007. Enzymatic transition state theory and transition state analog design. J. Biol. Chem. 282:28297–
Pauling, L. 1948. Nature of forces between large molecules of biological interest. Nature 161:707–
Leinhard, G. E. 1973. Enzymatic catalysis and transition-
Kraut, J. 1988. How do enzymes work? Science 242:533–
Waxman, D. J., and Strominger, J. L. 1983. Penicillin-
Abraham, E. P. 1981. The β-lactam antibiotics. Sci. Am. 244(6):76–
Walsh, C. T. 1984. Suicide substrates, mechanism-
Hilvert, D. 2000. Critical analysis of antibody catalysis. Annu. Rev. Biochem. 69:751–
Wade, H., and Scanlan, T. S. 1997. The structural and functional basis of antibody catalysis. Annu. Rev. Biophys. Biomol. Struct. 26:461–
Lerner, R. A., Benkovic, S. J., and Schultz, P. G. 1991. At the crossroads of chemistry and immunology: Catalytic antibodies. Science 252:659–
Cochran, A. G., and Schultz, P. G. 1990. Antibody-
Hammes, G. G., Benkovic, S. J., and Hammes-
Johnson, K. A., and Goody, R. S. 2011. The Original Michaelis Constant: Translation of the 1913 Michaelis−Menten Paper. Biochemistry 50:8264–
Hammes-
Benkovic, S. J., and Hammes-
Hur, S., and Bruice, T. C. 2003. The near attack conformation approach to the study of the chorismate to prephenate reaction. Proc. Natl. Acad. Sci. U.S.A. 100:12015–
Miles, E. W., Rhee, S., and Davies, D. R. 1999. The molecular basis of substrate channeling. J. Biol. Chem. 274:12193–
Warshel, A. 1998. Electrostatic origin of the catalytic power of enzymes and the role of preorganized active sites. J. Biol. Chem. 273:27035–
Cannon, W. R., and Benkovic, S. J. 1999. Solvation, reorganization energy, and biological catalysis. J. Biol. Chem. 273:26257–
Cleland, W. W., Frey, P. A., and Gerlt, J. A. 1998. The low barrier hydrogen bond in enzymatic catalysis. J. Biol. Chem. 273: 25529–
Romesberg, F. E., Santarsiero, B. D., Spiller, B., Yin, J., Barnes, D., Schultz, P. G., and Stevens, R. C. 1998. Structural and kinetic evidence for strain in biological catalysis. Biochemistry 37:14404–
Fersht, A. R., Leatherbarrow, R. J., and Wells, T. N. C. 1986. Binding energy and catalysis: A lesson from protein engineering of the tyrosyl-
Jencks, W. P. 1975. Binding energy, specificity, and enzymic catalysis: The Circe effect. Adv. Enzymol. 43:219–
Knowles, J. R., and Albery, W. J. 1976. Evolution of enzyme function and the development of catalytic efficiency. Biochemistry 15:5631–
Allewell, N. M. 2010. Thematic Minireview Series: Single-
Min, W., English, B. P., Lou, G., Cherayil, B. J., Kou, S. C., and Xie, X. S. 2005. Fluctuating Enzymes: Lessons from Single-
Xie, X. S., and Lu, H. P. 1999. Single-
Lu, H. P., Xun, L., and Xie, X. S. 1998. Single-