KEY TERMS

pump

carrier

channel

active transport

facilitated diffusion (passive transport)

ATP-driven pump

primary active transport

secondary active transport

simple diffusion

electrochemical potential (membrane potential)

Na+–K+ pump (Na+–K+ATPase)

sarcoplasmic reticulum Ca2+ ATPase (SERCA)

gastric H+–K+ ATPase

P-type ATPase

eversion

cardiotonic steroid

digitalis

multidrug resistance

multidrug-resistance (MDR) protein (P-glycoprotein)

ATP-binding cassette (ABC) domain

ABC transporter

secondary transporter (cotransporter)

antiporter

symporter

uniporter

lactose permease

ion channel

nerve impulse

action potential

patch-clamp technique

gigaseal

selectivity filter

voltage-gated channel

ball-and-chain model

neurotransmitter

acetylcholine

synaptic cleft

acetylcholine receptor

ligand-gated channel

equilibrium potential

Nernst equation

long QT syndrome (LQTS)

gap junction (cell-to-cell channels)

connexin

connexon (hemichannel)

aquaporin