KEY TERMS

template

DNA polymerase

primer

exonuclease

primase

replication fork

Okazaki fragment

lagging strand

leading strand

857

DNA ligase

helicase

supercoiling

linking number

topoisomer

twist

writhe

topoisomerase

processivity

sliding clamp

trombone model

origin of replication

origin of replication complex (ORC)

cell cycle

telomere

telomerase

mutagen

mismatch repair

direct repair

base-excision repair

nucleotide-excision repair

nonhomologous end joining (NHEJ)

trinucleotide repeat

tumor-suppressor gene

Ames test

RecA

Holliday junction

recombinase

recombination synapse