ligand

dissociation constant (K_d)

side effect

inhibition constant (K_i)

Cheng–Prusoff equation

ADME

oral bioavailability

Lipinski’s rules

compartment

blood–brain barrier

xenobiotic compounds

drug metabolism

oxidation

conjugation

phase I transformation

phase II transformation

first-pass metabolism

glomeruli

enterohepatic cycling

therapeutic index

atheroma

myopathy

high-throughput screening

combinatorial chemistry

split-pool synthesis

structure-based drug design

structure–activity relationship (SAR)

placebo

placebo effect