Because the short-term parking lot was full, Miranda had to use the park-and-ride lot and almost missed her plane.
The short-term parking lot was full, Miranda had to use the park-and-ride lot and almost missed her plane.
The second sentence is a run-on because two independent clauses are joined with only a comma. The first sentence corrects the error by making the first independent clause subordinate with the subordinating conjunction Because.
For more help, see section 20.