When ingested, sucrose (table sugar) is digested into equal parts glucose and fructose. In muscle, fructose is phosphorylated by hexokinase into fructose 6-phosphate and then proceeds into glycolysis via phosphofructokinase.
3.
What is the standard free-energy change for the conversion of one mole of sucrose into lactate? Use the data given in Table 16.1 and the fact that ΔG°' = -25 kJ/mol for the fermentation of pyruvate into lactate. Assume that the standard free energy of the hexokinase reaction is the same for all substrates.
What is the nonstandard free-energy change for the conversion of one mole of sucrose into lactate when the concentrations of reactants are: 7 mM sucrose; 0.1 mM lactate; 4 mM ATP; 0.5 mM ADP; and 3 mM Pi?