Chapter 40. Problem 40.6

Problem-Solving Video Assessment
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Problem 40.6: The Price of Protein Synthesis

1.

How many ATP molecules are used to synthesize a 755-residue protein, starting from amino acids? Assume that hydrolysis of PPi is equivalent to hydrolysis of ATP for this calculation.

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_feedback_correct: Correct. _feedback_incorrect: Incorrect.

2.

How many GTP molecules are used to synthesize an 86-residue protein, starting from amino acids?

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_feedback_correct: Correct. _feedback_incorrect: Incorrect.

3.

In total, 499 nucleotide triphosphate molecules (ATP/PPi and GTP) are used to synthesize a protein, starting from amino acids. How many amino acids does this protein contain?

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_feedback_correct: Correct. _feedback_incorrect: Incorrect.

4.

Imagine an mRNA transcript that normally codes for an 893-residue protein. If the transcript develops a mutation at residue 27 that changes the codon to UAG, how many ATP molecules will be used to translate this mRNA into protein, starting from amino acids? Assume that hydrolysis of PPi is equivalent to hydrolysis of ATP for this calculation.

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_feedback_correct: Correct. _feedback_incorrect: Incorrect.

5.

Imagine an mRNA transcript that starts with AUG and ends with UAA. The total length of the mRNA is 963 nucleotides. How many GTP molecules are used to translate this mRNA into protein, starting from amino acids?

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_feedback_correct: Correct. _feedback_incorrect: Incorrect.

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