WEBVTT 1 00:00:06.000 --> 00:00:13.750 Alcohol is a depressant, and it is used more than any other psychoactive drug other than caffeine. 2 00:00:13.750 --> 00:00:20.000 Alcohol is generally produced by fermenting grain or fruit. 3 00:00:20.000 --> 00:00:30.500 Although alcohol is classified as a depressant, many people believe that in small doses, alcohol acts as a stimulant. 4 00:00:30.500 --> 00:00:41.000 In small doses, alcohol does reduce normal inhibitions and allow behaviors, aggressive or sexual, to be exhibited. 5 00:00:41.000 --> 00:00:47.000 In moderate doses, it often produces mild euphoria or relaxation, 8 00:01:03.500 --> 00:01:15.000 Alcohol has many impacts in the brain. Its primary effect is to increase the binding of the neurotransmitter GABA. 9 00:01:15.000 --> 00:01:25.000 GABA is the most common inhibitory neurotransmitter in the brain, and by causing this neurotransmitter to bind more 10 00:01:25.000 --> 00:01:30.000 it is the principal way that alcohol acts as a depressant 11 00:01:30.000 --> 00:01:39.750 One of the regions of the brain affected is the forebrain, which is where alcohol can impact judgement and concentration. 12 00:01:39.750 --> 00:01:51.000 Another way alcohol impacts the brain is to reduce the binding of the neurotransmitter Glutamate, particularly in the hippocampus. 13 00:01:51.000 --> 00:01:58.000 It is probably this effect on the brain that is most important in impacting memory.