WEBVTT 1 00:00:06.000 --> 00:00:14.000 Although technically classified as a hallucinogen, marijuana has some similarities to depressants. 2 00:00:14.000 --> 00:00:20.000 For example, marijuana users often report a feeling of relaxation. 3 00:00:20.000 --> 00:00:27.950 Marijuana also tends to lower blood pressure and depress the functioning of the digestive system. 4 00:00:27.950 --> 00:00:36.000 Like Alcohol, marijuana reduces people's inhibitions and impairs memory and motor skills. 5 00:00:36.000 --> 00:00:44.000 Marijuana may also depress male sex hormones and hasten the loss of brain cells. 6 00:00:52.000 --> 00:00:59.900 Researchers have discovered that the active ingredient in marijuana, a compound called THC 7 00:00:59.900 --> 00:01:10.250 mimics natural substances in the brain, called cannabinoids that control the release of the neurotransmitter dopamine. 8 00:01:10.250 --> 00:01:20.000 THC and the natural cannabinoid work through indirect means to increase the amount of dopamine released. 9 00:01:28.000 --> 00:01:33.500 In particular, regions of the limbic system are involved. 10 00:01:33.500 --> 00:01:40.000 One area of the limbic system that is most particularly affected is the hippocampus 11 00:01:40.000 --> 00:01:46.000 which is important in the making our short-term memories permanent.