WEBVTT 1 00:00:00.000 --> 00:00:08.000 In our first drug, it has the ability to bind as well as the actual neurotransmitters. 2 00:00:08.000 --> 00:00:20.000 So with the drug, many more of the receptors on the postsynaptic neuron will be bound to and activated than without the drug 3 00:00:20.000 --> 00:00:26.500 So overall the synapse is more active than without the drug.