WEBVTT

1
00:00:05.000 --> 00:00:12.000
Lets review.  Destroying the ventromedial region of the hypothalamus produces a very fat rat.

2
00:00:12.000 --> 00:00:19.000
Destroying the lateral region of the hypothalamus produces a rat that will starve if not force fed

3
00:00:19.000 --> 00:00:24.000
Even then, the rat will never regain its normal weight

4
00:00:24.000 --> 00:00:29.000
Stimulating these regions generally produces the opposite effect of destruction

5
00:00:29.000 --> 00:00:36.000
Interestingly rats with the destruction of the ventromedial hypothalamus do not gain weight forever

6
00:00:36.000 --> 00:00:42.000
nor do rats with damage to the lateral hypothalamus continue to lose weight

7
00:00:42.000 --> 00:00:48.000
After a time, they establish a new stable weight called a set point

8
00:00:48.000 --> 00:00:61.000
Researchers have concluded that these areas of the hypothalamus are part of a large network of brain structures that interact to control hunger and maintain a stable body weight