WEBVTT 1 00:00:04.000 --> 00:00:09.000 Scattered throughout the axon membrane are sodium channels and potassium channels. 2 00:00:09.000 --> 00:00:12.500 Ions diffuse through these channels. 3 00:00:13.000 --> 00:00:18.000 Sodium/potassium pumps capture ions and actively push them through the membrane. 4 00:00:18.000 --> 00:00:23.000 The positively charged sodium ions are repelled by the other positive charges outside the axon, 5 00:00:23.000 --> 00:00:30.000 and attracted to the negative charges inside, but are kept out by the sodium gates in the cell membrane. 6 00:00:30.000 --> 00:00:36.000 When the neuron fires, the part of the axon nearest the cell body opens its sodium gates, 7 00:00:36.000 --> 00:00:39.000 allowing the sodium ions to rush in. 8 00:00:39.000 --> 00:00:49.000 The influx of these positively charged ions depolarizes that part of the axon making it electrically positive relative to the extracellular fluid. 9 00:00:49.000 --> 00:00:54.000 This in turn causes the next section of the axon to open its gates and become depolarized, 10 00:00:54.000 --> 00:01:01.000 and the electrical impulse - called the action potential - moves down the axon like a wave. 11 00:01:01.000 --> 00:01:08.000 By this time (about 1/2 millisecond later) the sodium gates in the first section of the axon close up again. 12 00:01:08.000 --> 00:01:15.000 Other gates open to allow some of the potassium ions, repelled by the sudden positive shift, 13 00:01:15.000 --> 00:01:19.000 to flow out of the axon, therefore repolarizing the membrane.