figure 16.3 Brain activity and schizophrenia The image shows areas in which brain activity in people with and without schizophrenia differed while performing a task that placed demands on the working memory system. The yellow-orange areas are those in which people with schizophrenia had less brain activity than others. The purple-pinkish areas are ones in which they showed greater activity. Differences between groups of people, then, were complex. People with schizophrenia did not have less brain activity across all regions of the brain but did have less activity in regions of the brain known to be involved in memory performance.