Describe the sequence of events within the neuron that produces an action potential.
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1. When a neuron is stimulated, it "fires," sending a neural impulse down its axon from the cell body to the axon terminals.
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2. The neural impulse is actually a brief electrical charge called an action potential. Action potentials are generated by the movement of positively charged ions in and out of the axon.
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3. In its resting state, the interior of the axon is electrically negative. As the action potential travels down the axon, each tiny section of the axon opens its sodium channels, allowing positively charged sodium ions to flow into the axon. For a brief moment, that section of the axon becomes electrically positive.
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4. Soon, potassium channels open, and then the positive charge decreases as positive potassium ions flow out of the axon.
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5. As the action potential moves further down the axon, the original section of the axon returns to its resting state, as special sodium-potassium pumps restore the original concentrations of sodium and potassium ions.
Practice 1: Generating an Action Potential
Play the animation to watch the sequence of events in an action potential.
Practice 2: Measuring the Action Potential
Select the PLAY button to measure the electrical charge before and after the action potential.
Researchers can use a tiny electrode (connected to a voltmeter) to measure the electrical charge at a particular axon location.
Researchers then stimulate the axon to produce an action potential. Note the change in the axon’s electrical charge as the action potential sweeps past that location on the axon.
Quiz 1
Drag each description to the appropriate gray area to form the correct sequence of events that occurs when an action potential is generated. When all the descriptions have been placed, select the CHECK ANSWER button.
Quiz 2
Match the terms to their descriptions by dragging each colored circle to the appropriate gray circle. When all the circles have been placed, select the CHECK ANSWER button.