General

Friedberg, E.C. 2007. A brief history of the DNA repair field. Cell Res. 18:3–7. An excellent overview of DNA repair over the past 50 or more years.

Hanawalt, P.C. 2007. Paradigms for the three Rs: DNA replication, recombination, and repair. Mol. Cell 28:702–707.

Types of DNA Mutations

Abeysinghe, S.S., N. Chuzhanova, and D.N. Cooper. 2006. Gross deletions and translocations in human genetic disease. Genome Dyn. 1:17–34.

Dion, V., and J.H. Wilson. 2009. Instability and chromatin structure of expanded trinucleotide repeats. Trends Genet. 25:288–297.

Maki, H. 2002. Origins of spontaneous mutations: Specificity and directionality of base-substitution, frameshift, and sequence-substitution mutageneses. Annu. Rev. Genet. 36:279–303.

Orr, H.T., and H.Y. Zoghbi. 2007. Trinucleotide repeat disorders. Annu. Rev. Neurosci. 30:575–621.

Seo, K.Y., S.A. Jelinsky, and E.L. Loechler. 2000. Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens. Mutat. Res. 463:215–246.

DNA Alterations That Lead to Mutations

Batista, L.F., B. Kaina, R. Meneghini, and C.F. Menck. 2009. How DNA lesions are turned into powerful killing structures: Insights from UV-induced apoptosis. Mutat. Res. 681:197–208.

Deweese, J.E., and N. Osheroff. 2009. The DNA cleavage reaction of topoisomerase II: Wolf in sheep’s clothing. Nucleic Acids Res. 37:738–748.

Friedberg, E.C., G.C. Walker, W. Siede, R.D. Wood, R.A. Schultz, and T. Ellenberger. 2006. DNA Repair and Mutagenesis, 2nd ed. Washington, DC: American Society for Microbiology.

Ohnishi, T., E. Mori, and A. Takahashi. 2009. DNA double-strand breaks: Their production, recognition, and repair in eukaryotes. Mutat. Res. 669:8–12.

Mechanisms of DNA Repair

Cleaver, J.E. 2003. Classics in DNA repair: Photoreaction. DNA Repair (Amst.) 2:629–638. The dispute arising over priority in the discovery of photoreactivation is revisited and placed in perspective.

Cox, M.M. 2007. Regulation of bacterial RecA protein function. Crit. Rev. Biochem. Mol. Biol. 42:41–63.

Goodman, M.F., and B. Tippin. 2000. Sloppier copier DNA polymerases involved in genome repair. Curr. Opin. Genet. Dev. 10:62–168.

Heller, R.C., and K.J. Marians. 2006. Replisome assembly and the direct restart of stalled replication forks. Nat. Rev. Mol. Cell Biol. 7:932–943.

McCulloch, S.D., and T.A. Kunkel. 2008. The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res. 18:148–161. An excellent summary of translesion polymerases.

Sancar, A., L.A. Lindsey-Boltz, K. Unsal-Kaçmaz, and S. Linn. 2004. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem. 73:39–85.