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Overalyed!!
Overalyed!!
Overalyed!!
Overalyed!!
Overalyed!!
Click on the attacking nucleophile.
Great—now click on the atom it attacks.
Simulating....
DNA Pol senses the incorrect base pairing, and is stalled. Click on the activity that will proofread the incorrect nucleotide.
Click on the attacking nucleophile.
Great! Now click on the molecule it is attacking.

Objective

Create a double-stranded DNA using DNA polymerase, and understand the chemistry behind the polymerization reaction and the polymerase proofreading mechanism.

Reward

Collect the DNA Polymerase token and unlock the DNA Replication simulation marker.