A depression switch? By comparing the brains of patients with and without depression, researcher Helen Mayberg identified a brain area (highlighted in red) that appears active in people who are depressed or sad, and whose activity may be calmed by deep brain stimulation.
Helen Mayberg, M.D. Psychiatric Neuroimaging and Therapeutics, The Mayberg Lab at Emory University, Atlanta, GA/V. J. Wedeen and L. L. Wald/Athinoula A. Martinos Center For Biomedical Imaging and The Human Connectome Project, Boston, MA