Table 13-1: Examples of Drosophila A–P Axis Genes That Contribute to Pattern Formation

Gene symbol

Gene Name

Protein function

Role(s) in early development

hb-z

hunchback-zygotic

Transcription factor—zinc-finger protein

Gap gene

Kr

Krüppel

Transcription factor—zinc-finger protein

Gap gene

kni

knirps

Transcription factor—steroid receptor-type protein

Gap gene

eve

even-skipped

Transcription factor—homeodomain protein

Pair-rule gene

ftz

fushi tarazu

Transcription factor—homeodomain protein

Pair-rule gene

opa

odd-paired

Transcription factor—zinc-finger protein

Pair-rule gene

prd

paired

Transcription factor—PHOX protein

Pair-rule gene

en

engrailed

Transcription factor—homeodomain protein

Segment-polarity gene

wg

wingless

Signaling WG protein

Segment-polarity gene

hh

hedgehog

Signaling HH protein

Segment-polarity gene

ptc

patched

Transmembrane protein

Segment-polarity gene

lab

labial

Transcription factor—homeodomain protein

Segment-identity gene

Dfd

Deformed

Transcription factor—homeodomain protein

Segment-identity gene

Antp

Antennapedia

Transcription factor—homeodomain protein

Segment-identity gene

Ubx

Ultrabithorax

Transcription factor—homeodomain protein

Segment-identity gene