Signaling-Pathway Components

      Wingless

armadillo

β-catenin

Colon and skin

D.TCF

TLF

Colon

      Hedgehog

cubitus interruptus

Glil

Basal-cell carcinoma

patched

patched

Basal-cell-carcinoma, medulloblastoma

smoothened

smoothened

Basal-cell carcinoma

      Notch

Notch

hNotchl

Leukemia, lymphoma

      EGF receptor

torpedo

C-erbB-2

Breast and colon

      Decapentaplegic/TFG-β

Medea

DPC4

Pancreatic and colon

      Toll

dorsal

NF-kB

Lymphoma

Other

extradenticle

Pbxl

Acute pre-B-cell leukemia