• Significance tests and confidence intervals for the mean μ of a Normal population are based on the sample mean of an SRS. Because of the central limit theorem, the resulting procedures are approximately correct for other population distributions when the sample is large.
• The standard error of the sample mean is
• The standardized sample mean, or one-sample z statistic,
has the N(0, 1) distribution. If the standard deviation of is replaced by the standard error , the one-sample t statistic
has the t distribution with n − 1 degrees of freedom.
• There is a t distribution for every positive degrees of freedom k. All are symmetric distributions similar in shape to Normal distributions. The t(k) distribution approaches the N(0, 1) distribution as k increases.
• A level C confidence interval for the mean μ of a Normal population is
where t* is the value for the t(n − 1) density curve with area C between −t* and t*. The quantity
is the margin of error.
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• Significance tests for H0: μ = μ0 are based on the t statistic. P-values or fixed significance levels are computed from the t(n − 1) distribution.
• A matched pairs analysis is needed when subjects or experimental units are matched in pairs or when there are two measurements on each individual or experimental unit and the question of interest concerns the difference between the two measurements.
• The one-sample procedures are used to analyze matched pairs data by first taking the differences within the matched pairs to produce a single sample.
• One-sample equivalence testing assesses whether a population mean μ is practically different from a hypothesized mean μ0. This test requires a threshold δ, which represents the largest difference between μ and μ0 such that the means are considered equivalent.
• The t procedures are relatively robust against non-Normal populations. The t procedures are useful for non-Normal data when unless the data show outliers or strong skewness. When , the t procedures can be used even for clearly skewed distributions.