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Prerequisite skills needed:

  • RNA Structure
  • Relevant book section: pages 1101-1110

By completing this simulation, you will:

  • Understand the chemical reactions of translation
  • Understand the sequence of events and process of translation
  • Build a bacterial ribosome
  • Translate a portion of mRNA
  • Terminate translation and recycle the ribosome
Peptide Bond Formation This is the first time you have created a peptide bond. In our simulation, this step has been simplified. To see the details, please click Peptide Bond Formation below. Click Dismiss to continue with the activity.

Instructions

Your task in this simulation is to translate this mRNA. Begin by assembling the initiation complex on the transcript. Drag and drop the appropriate molecules to the correct area to assemble the complex.

Hint: The small subunit of the ribosome requires additional factors before it can associate with mRNA. Also, if you need any tRNA molecules, please click on the red amino acid to activate the tRNA builder.
Congratulations Now that you have assembled the initiation complex, use the tRNA builder and the shown molecules to elongate the amino acid chain. When appropriate, terminate the translation process and recycle the ribosome.
Congratulations You have successfully completed this activity!
Amino Acid (ex. ALA)
3'--5'
Anti-Codon (ex. GAA)

Not Valid

Not Valid. Try fMet instead.

RNA Processing - Simulation Results

Your Answer:
Correct Answer:
NOTE: This is not the actual sequence of the BRCA-II gene, but rather just a random sequence created for this exercise.

Results:

Congratulations! You figured out the sequence based on the chromatogram. If you would like to try the exercise again with a new dna sequence, please click the button below.

Results:

Sorry, you selected the wrong nucleotides. If you would like to try the exercise again with a new dna sequence, please click the button below.