Figure 5.20A The Role of Microfilaments in Cell Movement—
Original Paper: Pollard, T. D and R. R. Weihing. 1974. Actin and myosin in cell movement. CRC Critical Reviews of Biochemistry 2:
After a test tube demonstration that the drug cytochalasin B prevented microfilament formation from monomeric precursors, the question was asked: Will the drug work like this in living cells and inhibit cell movement in Amoeba? Complementary experiments showed that the drug did not poison other cellular processes.