Figure 13.2 Genetic Transformation by DNA

Original Paper: Avery, O. T., C. M. MacLeod and M. McCarty. 1944. Studies on the chemical nature of the substance inducing transformation of the pneumococcal types. Journal of Experimental Medicine 79: 137–158.

Experiments by Avery and his colleagues showed that DNA from the virulent S strain of pneumococcus was responsible for the transformation in Griffith’s experiments (see Figure 13.1).