The extracellular matrix supports tissue functions in animals

Animal cells lack the semirigid wall that is characteristic of plant cells, but many animal cells are surrounded by, or in contact with, an extracellular matrix. This matrix is composed of three types of molecules: fibrous proteins such as collagen (the most abundant protein in mammals, constituting over 25 percent of the protein in the human body); a matrix of glycoproteins termed proteoglycans, consisting primarily of sugars; and a third group of proteins that link the fibrous proteins and the gel-like proteoglycan matrix together (Figure 5.22). These proteins and proteoglycans are secreted, along with other substances that are specific to certain body tissues, by cells that are present in or near the matrix.

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Figure 5.22 An Extracellular Matrix Cells in the kidney secrete a basal lamina, which is an extracellular matrix that separates the kidney cells from a nearby blood vessel. The basal lamina filters materials that pass between the kidney and the blood.

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The functions of the extracellular matrix are many: