Allosteric Regulation of Enzymes

Question 1 of 4

Animation 8.2 Quiz

A _______ allosteric regulator _______ the rate of an enzyme-catalyzed reaction by inducing the active site of the enzyme to become _______.

negative; increases; hidden

positive; increases; exposed

positive; decreases; hidden

negative; decreases; exposed

Correct. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Incorrect. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Animation 8.2 Quiz

How do allosteric regulators affect their target enzymes?

By binding to the enzyme’s active site and blocking the binding of substrate molecules to the enzyme

By inducing amino acid side chain substitutions at a site other than the active site, causing a conformational change in the enzyme

By binding to the enzyme’s active site and causing a conformational change in the enzyme

By binding to a site other than the active site and causing a conformational change in the enzyme

Correct. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Incorrect. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Animation 8.2 Quiz

Cite a reason for the evolution of allosteric regulators in cells.

They allow the cell to conserve energy by shutting down or activating reaction pathways only as needed.

They allow the cell to use many fewer enzymes to carry out a wide range of reactions.

They allow the cell to carry out reactions at relatively low temperatures and mild pH conditions.

They allow the cell to have a means for transferring information as it undergoes cell division to produce a new generation of cells.

Correct. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Incorrect. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Animation 8.2 Quiz

Refer to the table below.

The effects of two compounds, X and Z, on an enzyme’s catalytic activity are analyzed. Both compounds are known to bind to the enzyme, but not at the enzyme’s active site. Which statement is consistent with these data?

Both Compound X and Compound Z are allosteric inhibitors.

Both Compound X and Compound Z are allosteric activators.

Compound X is an allosteric activator and Compound Z is an allosteric inhibitor.

Compound X is an allosteric inhibitor and Compound Z is an allosteric activator.

Correct. See Key Concept 8.5 Enzyme Activities Can Be Regulated

Incorrect. See Key Concept 8.5 Enzyme Activities Can Be Regulated

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Chapter 1. Allosteric Regulation of Enzymes