FIGURE 1-22 Each eukaryotic organism used in cell biology has advantages for certain types of studies. The yeast Saccharomyces cerevisiae (a) has the cellular organization of a eukaryote but is a relatively simple single-celled organism that is easy to grow and to manipulate genetically. The green alga Chlamydomonas reinhardtii (b) is widely used to study photosynthesis and the structure and function of flagella. In the roundworm Caenorhabditis elegans (c), which has a small number of cells arranged in a nearly identical way in every worm, the formation of each individual cell can be traced. The fruit fly Drosophila melanogaster (d), first used to discover the properties of chromosomes, has been especially valuable in identifying genes that control embryonic development. Many of these genes are evolutionarily conserved in humans. Planaria (e) are flatworms that can regenerate any part of the body that is cut off, including the head and the photoreceptors. The stem cells that give rise to their new cells and tissues are widely studied. The zebrafish Danio rerio (f) is used for rapid genetic screens to identify genes that control vertebrate development and organogenesis. Of the experimental animal systems, mice (Mus musculus) (g) are evolutionarily the closest to humans and have thus provided models for studying numerous human genetic and infectious diseases. The mustard-family weed Arabidopsis thaliana (h) has been used for genetic screens to identify genes involved in nearly every aspect of plant life.
[Part (a) Scimat/Photo Researchers, Inc. Part (b) William Dentler University of Kansas. Part (c) Science Source. Part (d) Darwin Dale/Science Source. Part (e) Peter Reddien, MIT Whitehead Institute. Part (f) blickwinkel/Hartl/Alamy. Part (g) J. M. Labat/Jacana/Photo Researchers, Inc. Part (h) Darwin Dale/Science Source.]