FIGURE 18-34 Intraflagellar transport. (a) Particles are transported between the plasma membrane and the outer doublet microtubules. Transport of the particles to the tip is dependent on kinesin-2, whereas transport toward the base is mediated by cytoplasmic dynein. (b) This thin-section electron micrograph shows IFT particles in a section of a Chlamydomonas flagellum.

[Part (b) reprinted by permission from Macmillan Publishers Ltd: Rosenbaum J.L., and Witman, G.B., “Intraflagellar transport,” Nature Reviews Molecular Cell Biology, 2002, 3, 813-825.]