FIGURE 19-27 Model for reassembly of the nuclear envelope during telophase. Extensions of the endoplasmic reticulum (ER) associate with each decondensing chromosome and then fuse with one another, forming a double membrane around the chromosome. Dephosphorylated nuclear pore subcomplexes reassemble into nuclear pores, forming individual mini-nuclei called karyomeres. The enclosed chromosome further decondenses, and subsequent fusion of the nuclear envelopes of all the karyomeres at each spindle pole forms a single nucleus containing a full set of chromosomes. NPC, nuclear pore complex. See B. Burke and J. Ellenberg, 2002, Nature Rev. Mol. Cell Biol. 3:487.