FIGURE 5-23 Comparison of the common core structure at the center of ribosomes from all domains of life and bacterial, yeast, and human ribosomes. (a) RNA in the common core structure is shown in light blue and protein domains common to all ribosomes are shown in pink. Additions to the common core structure are shown in dark blue for RNA and red for proteins in ribosomes from T. thermophilus (b) and S. cerevisiae (c). Human ribosome structure (d) from cryoelectron microscopy. A tRNA visible in the E site is shown in green.

[Data for (a, b, c) from G. Yusupova and M. Yusupov, 2014, Annu. Rev. Biochem. 83:467; data for (d) from H. Khatter et al., 2015, Nature 520:640; PDB ID 4ug0.]