FIGURE 8-32 Model of SMC complexes bound to chromatin. (a) Model of an SMC protein complex. (b) Model of SMC complex topologically linking two 30-nm chromatin fibers (represented by cylinders). (c) Model for the binding of SMC complexes to the base of a loop of transcribed chromatin. See K. Nasmyth and C. H. Haering, 2005, Ann. Rev. Biochem. 74:595.