Receptor-
Some extracellular ligands that bind to specific cell-
Sorting signals in the cytosolic domain of cell-
665
The endocytic pathway delivers some ligands (e.g., LDL particles) to lysosomes, where they are degraded. Transport vesicles from the cell surface first fuse with late endosomes, which subsequently fuse with lysosomes.
Most receptor-
Iron is imported into cells by an endocytic pathway in which Fe3+ ions are released from ferrotransferrin in the late endosome. The receptor-