General References

Bray, D. 2001. Cell Movements. Garland.

Howard, J. 2001. The Mechanics of Motor Proteins and the Cytoskeleton. Sinauer Associates.

Kreis, T., and R. Vale. 1999. Guidebook to the Cytoskeletal and Motor Proteins. Oxford University Press.

Microfilaments and Actin Structures

Holmes, K. C., et al. 1990. Atomic model of the actin filament. Nature 347:44–49.

Kabsch, W., et al. 1990. Atomic structure of the actin:DNase I complex. Nature 347:37–44.

Pollard, T. D., and J. A. Cooper. 2009. Actin, a central player in cell shape and movement. Science 326:1208–1212.

Pollard, T. D., L. Blanchoin, and R. D. Mullins. 2000. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Ann. Rev. Biophys. Biomol. Struc. 29:545–576.

Dynamics of Actin Filaments

Paavilainen, V. O., et al. 2004. Regulation of cytoskeletal dynamics by actin-monomer-binding proteins. Trends Cell Biol. 14:386–394.

Theriot, J. A. 1997. Accelerating on a treadmill: ADF/cofilin promotes rapid actin filament turnover in the dynamic cytoskeleton. J. Cell Biol. 136:1165–1168.

Mechanisms of Actin Filament Assembly and Disassembly

Brieher, W. 2013. Mechanisms of actin disassembly. Mol. Biol. Cell 24:2299–2302.

Campellone, K. G., and M. D. Welch. 2010. A nucleator arms race: cellular control of actin assembly. Nature Rev. Mol. Cell Biol. 11:237–251.

Chen, B., et al. 2014. The WAVE regulatory complex links diverse receptors to the actin cytoskeleton. Cell 156:195–207.

Chesarone, M. A., et al. 2010. Unleashing formins to remodel the actin and microtubule cytoskeletons. Nature Rev. Mol. Cell Biol. 11:62–74.

Goode, B. L., and M. J. Eck. 2007. Mechanism and function of formins in the control of actin assembly. Ann. Rev. Biochem. 76:593–627.

Gouin, E., M. D. Welch, and P. Cossart. 2005. Actin-based motility of intracellular pathogens. Curr. Opin. Microbiol. 8:35–45.

Higgs, H. N. 2005. Formin proteins: a domain-based approach. Trends Biochem. Sci. 30:342–353.

Pruyne, D., et al. 2002. Role of formins in actin assembly: nucleation and barbed end association. Science 297:612–615.

Rotty, J. D., C. Wu, and J. E. Bear. 2013. New insights into the regulation and cellular functions of the Arp2/3 complex. Nature Rev. Mol. Cell Biol. 14:7–12.

Rouiller, I., et al. 2008. The structural basis of actin filament branching by the Arp2/3 complex. J. Cell Biol. 180:887–895.

Organization of Actin-Based Cellular Structures

Bennett, V., and A. J. Baines. 2001. Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. Physiol. Rev. 81:1353–1392.

Fehon, R. G., A. I. McClatchey, and A. Bretscher. 2010. Organizing the cell cortex: the role of ERM proteins. Nature Rev. Mol. Cell Biol. 11:276–287.

McGough, A. 1998. F-actin-binding proteins. Curr. Opin. Struc. Biol. 8:166–176.

Stossel, T. P., et al. 2001. Filamins as integrators of cell mechanics and signalling. Nature Rev. Mol. Cell Biol. 2:138–145.

Myosins: Actin-Based Motor Proteins

Berg, J. S., B. C. Powell, and R. E. Cheney. 2001. A millennial myosin census. Mol. Biol. Cell 12:780–794.

Mermall, V., P. L. Post, and M. S. Mooseker. 1998. Unconventional myosin in cell movement, membrane traffic, and signal transduction. Science 279:527–533.

Rayment, I. 1996. The structural basis of the myosin ATPase activity. J. Biol. Chem. 271:15850–15853.

Vale, R. D. 2003. The molecular motor toolbox for intracellular transport. Cell 112:467–480.

Vale, R. D., and R. A. Milligan. 2000. The way things move: looking under the hood of molecular motor proteins. Science 288:88–95.

Myosin-Powered Movements

Bretscher A. 2003. Polarized growth and organelle segregation in yeast—the tracks, motors, and receptors. J. Cell Biol. 160:811–816.

Clark, K. A., et al. 2002. Striated muscle cytoarchitecture: an intricate web of form and function. Ann. Rev. Cell Dev. Biol. 18:637–706.

Grazier, H. L., and S. Labeit. 2004. The giant protein titin: a major player in myocardial mechanics, signaling, and disease. Circ. Res. 94:284–295.

Hammer, J. A. III and J. R. Sellers. 2012. Walking to work: roles for class V myosins as cargo transporters. Nature Rev. Mol. Cell Biol. 13:13–26.

Cell Migration: Signaling and Chemotaxis

Artemenko, Y., T. J. Lampert, and P. N. Devreotes. 2014. Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes. Cell Mol. Life Sci. 71:3711–3747.

Borisy, G. G., and T. M. Svitkina. 2000. Actin machinery: pushing the envelope. Curr. Opin. Cell Biol. 12:104–112.

Burridge, K., and K. Wennerberg. 2004. Rho and Rac take center stage. Cell 116:167–179.

Etienne-Manneville, S. 2004. Cdc42—the centre of polarity. J. Cell Sci. 117:1291–1300.

Etienne-Manneville, S., and A. Hall. 2002. Rho GTPases in cell biology. Nature 420:629–635.

Manahan, C. L., et al. 2004. Chemoattractant signaling in Dictyostelium discoideum. Ann. Rev. Cell Dev. Biol. 20:223–253.

Pollard, T. D., and G. G. Borisy. 2003. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112:453–465.

Ridley, A. J., et al. 2003. Cell migration: integrating signals from the front to back. Science 302:1704–1709.

Small, J. V., et al. 2002. The lamellipodium: where motility begins. Trends Cell Biol. 12:112–120.