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Model Organisms and Methods of Studying the Cell Cycle
The ability to isolate mutants and the powerful genetic tools of budding and fission yeasts allowed for the isolation of key genetic factors important for cell cycle regulation.
Frog eggs and early embryos from synchronously fertilized eggs, which provide sources of extracts for biochemical studies of cell cycle events, allowed the identification of the oscillatory nature of cyclin-
Fruit flies are a powerful system for investigating the interplay between cell division and the developmental programs responsible for building multicellular organisms.
Human tissue culture cells are used to study the properties of the mammalian cell cycle.
The generation of synchronized cell populations by reversibly arresting cells in a particular cell cycle stage allows researchers to examine the behavior of proteins and cellular processes during the cell cycle.