Chapter 15. Cholera and cAMP
Introduction
Analyze the Data 15-3: Cholera and cAMP
Cyclic AMP is a second messenger that regulates many diverse cellular functions. In the intestinal lumen, it is responsible for maintaining electrolyte and water balance. Certain bacterial toxins, including one produced by Vibrio cholerae, can upset the levels of cAMP, leading to fatal dehydration.
Question
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Question
k+AKJy5TB1yslOgo1xnGQavWN+tB5dPBPHve5YcaFxFryqeLvnAKXM2wzePBb5m/u0l93HN7kTzWcytTKhXseKFZN5NusUaCoGQq2r8yjreUWebOaryVFxB2xPjQgyy0yWoa+7/nsuj3wuQIFxMqYsLmaQZFLZTUX696hkFmneyaQTRSZPC6oAaqVZzB99XJtsO6mSmRj6PN2VxX0pScfEmbT2D+9iuQHigher, because the abundant cAMP keeps PKA active, which subsequently leads to the activation of channels which indirectly causes water to follow the ions out of the cell.
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