Chapter 15. The IP3/DAG Pathway and the Elevation of Cytosolic Ca2⁺

Animation Activities

true

false

Animation Activity 15-34: The IP3/DAG Pathway and the Elevation of Cytosolic Ca2+

The catalytic activity of G protein–activated phospholipase C (PLC) generates two second messenger molecules: ________ and ________.

cAMP and Ca²⁺

PIP₂ and Ca²⁺

IP₃ and PIP₂

IP₃ and Ca²⁺

IP₃ and DAG

Correct.

Incorrect.

Try Again.

What is the direct target of IP₃ and the effect of IP₃ binding to its target?

plasma membrane Ca²⁺-ATPase; pumping of cytosolic Ca²⁺ out of the cell

store-operated Ca²⁺ channel; influx of extracellular Ca²⁺ into the cytosol

gated Ca²⁺ channel; pumping of cytosolic Ca²⁺ into the ER

gated Ca²⁺ channel; release of Ca²⁺ from the ER into the cytosol

ER Ca²⁺-ATPase; pumping of cytosolic Ca²⁺ into the ER

Correct.

Incorrect.

Try Again.

The second messenger DAG directly ________.

activates a plasma membrane Ca²⁺ ATPase

causes a rise in cytosolic Ca²⁺ concentration

activates IP₃

activates PKC

activates PLC

Correct.

Incorrect.

Try Again.

Activity results are being submitted...

Introduction