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Endothelium-Leukocyte Interactions: Activation, Binding, Rolling, and Extravasation

Chapter 20. Endothelium-Leukocyte Interactions: Activation, Binding, Rolling, and Extravasation

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Animation Activity 20-40: Endothelium-Leukocyte Interactions: Activation, Binding, Rolling, and Extravasation

The process by which leukocytes move into tissue toward a foreign invader is called:

infiltration.

extravasation.

inflammation.

bacterial infection.

leukocyte activation.

Correct.

Incorrect.

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Which of these proteins bind to the rolling leukocyte, causing it to adhere tightly to the endothelium?

integrins

PAF receptors

ICAMs

P-selections

selectins

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What would be expected to happen if activation of the integrins on the surface of leukocytes was prevented?

The leukocytes would continue to roll from endothelial cell to endothelial cell.

Extravasation would be prevented.

The integrins would not be able to bind to ICAM on the surface of endothelial cells.

Tight binding between the leukocyte and endothelial cells would be prevented.

All of the above

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Incorrect.

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