a1701_actin_polymerization

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Polymerization of actin in vitro illustrates several import properties of the polymerization process that occurs in cells. Which of the following is false about G-actin monomer polymerization into F-actin filaments in vitro?

The nucleation phase requires three G-actins to interact simultaneously to form a seed (nucleus) stable enough to favor addition of more monomers for filament elongation.

During the elongation phase, G-actin monomers add only to the (+)end of each actin filament.

During the steady state phase, the total amount of F-actin does not change but G-actins continue to add to and dissociate from both ends.

During the steady state phase, a specific concentration of actin, known as the critical concentration is always disassembled in the G-actin form despite continual addition and loss of actin monomers at both ends of each actin filament.

None of the above is false.

Correct.

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Chapter 17. Actin Polymerization

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