a2001_leukocyte

Question 1 of 4

The presence of an infection triggers leukocytes to move into tissues in a process called:

membrane blebbing

extravasation

exocytosis

white blood cell circulation

cytokinesis

Correct.

You have one more chance to answer the question correctly. Try again.

Incorrect.

Which of the following is/are NOT on the cell surface of endothelial cells during the extravasation process?

P-selectin

Platelet-activating factor (PAF)

P-selectin and PAF

PAF receptors and integrins

All of the above are on the cell surface of endothelial cells during the extravasation process.

Correct.

You have one more chance to answer the question correctly. Try again.

Incorrect.

Which of the following results in the activation of integrins on leukocytes?

Receptor binding to PAF

Receptor binding to P-selectin

Deactivation of PAF

P-selectin and PAF interactions

All of the above can activate integrins on leukocytes.

Correct.

You have one more chance to answer the question correctly. Try again.

Incorrect.

Which of the following causes leukocytes to stop rolling and to tightly adhere to the endothelium?

activated integrins binding ICAM molecules constitutively expressed on the surface of endothelial cells

activated P-selectin binding ICAM molecules constitutively expressed on the surface of endothelial cells

activated integrins binding P-selectin molecules constitutively expressed on the surface of endothelial cells

deactivated PAF binding ICAM molecules constitutively expressed on the surface of endothelial cells

deactivated integrins binding ICAM molecules constitutively expressed on the surface of endothelial cells

Correct.

You have one more chance to answer the question correctly. Try again.

Incorrect.

Chapter 20. Cell-Cell Adhesion in Leukocyte Extravasation