The fourteenth and early fifteenth centuries were certainly times of crisis in western Europe. Famine, disease, and war decimated the European population, and traditional institutions, including secular governments and the church, did little or nothing or, in some cases, made things worse. Trading connections that had been reinvigorated in the High Middle Ages spread the most deadly epidemic ever experienced through western Asia, North Africa, and almost all of Europe.

The plague did not destroy the prosperity of the medieval population, however, and it may in fact have indirectly improved the European economy. Wealthy merchants had plenty of money to spend on luxuries and talent. In the century after the plague, Italian artists began to create new styles of painting, writers to pen new literary forms, educators to found new types of schools, and philosophers to develop new ideas about the purpose of human life. These cultural changes eventually spread to the rest of Europe, following the same paths that the plague had traveled.