FIG. 10.20 Cell shape determined by the structure of the extracellular matrix. Fibroblasts adopt different shapes depending on whether they are grown on a two-dimensional or a three-dimensional matrix.

Photo source: F. Tao, S. Chaudry, B. Tolloczko, J. G. Martin, and S. M. Kelly Modulation of smooth muscle phenotype in vitro by homologous cell substrate Am J Physiol Cell Physiol June 1, 2003 284:(6) C1531-C1541; published ahead of print March 5, 2003, doi:10.1152/ajp.