Feature |
siRNA |
miRNA |
Origin |
mRNA, transposon, or virus |
RNA transcribed from distinct gene |
Cleavage of |
RNA duplex or single-stranded RNA that forms long hairpins |
Single-stranded RNA that forms short hairpins of double-stranded RNA |
Size |
21–25 nucleotides |
21–25 nucleotides |
Action |
Degradation of mRNA, inhibition of transcription, chromatin modification |
Degradation of mRNA, inhibition of translation, chromatin modification |
Target |
Genes from which they were transcribed |
Genes other than those from which they were transcribed |