Repair System | Type of Damage Repaired |
---|---|
Mismatch | Replication errors, including mispaired bases and strand slippage |
Direct | Pyrimidine dimers; other specific types of alterations |
Base excision | Abnormal bases, modified bases, and pyrimidine dimers |
Nucleotide excision | DNA damage that distorts the double helix, including abnormal bases, modified bases, and pyrimidine dimers |
Homologous recombination | Double-strand breaks |
Nonhomologous end joining | Double-strand breaks |