Gene Where Expressed Action of Gene Product
dorsal Ovary Affects the expression of genes such as twist and decapentaplegic
cactus Ovary Traps Dorsal protein in the cytoplasm
toll Ovary Leads to the phosphorylation of Cactus, which is then degraded, releasing Dorsal to move into the nuclei of ventral cells
twist Embryo Takes part in the development of mesodermal tissues*
decapentaplegic Embryo Takes part in the development of gut structures
*One of the three primary tissue layers in the early embryo.
Table 22.2: Key genes that control the development of the dorsal–ventral axis in fruit flies and their action