Gene	Normal function	Cancer in which gene is mutated
APC	Scaffold protein, interacts with microtubules	Colorectal
BRCA1	DNA repair, transcription factor	Breast and ovarian
CDKN2A	Regulates cell division	Melanoma
NF1	GTpase activator	Neurofibromatosis
p53	Regulates cell division	Many types of cancer
RB	Regulates cell division	Retinoblastoma